GSM4057549[Accession] - GEO DataSets

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Items: 4

Select item 2001367641.

Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL18573
32 Samples

Download data: BROADPEAK, BW, NARROWPEAK

Series

Accession:: GSE136764

ID:: 200136764

PubMed Full text in PMC Similar studies

Select item 2001367632.

Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq]

(Submitter supplied) Endogenous retroviruses (ERVs) and other transposons can act as tissue-specific regulators of gene expression in cis, with potential to affect biological processes. In cancer, epigenetic alterations and transcription factor misregulation may uncover the regulatory potential of typically repressed ERVs, which could contribute to tumour evolution and progression. Here, we asked whether transposons help to rewire oncogenic transcriptional circuits in acute myeloid leukaemia (AML). more...