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Items: 3

1.

FOXO and HSF1 rejuvenate immunity via positive feedback regulation of insulin/IGF-1 signaling

(Submitter supplied) A hallmark of aging is immunosenescence, a decline in immune function that appeared to be inevitable. Surprisingly, here we show that genetic inhibition of DAF-2/insulin/IGF-1 receptor drastically delays immunosenescence and even rejuvenates immunity in C. elegans. We find that p38 mitogen activated protein kinase (PMK-1), a key determinant of immunosenescence in wild-type, is dispensable for this rejuvenated immunity. more...
Organism:
Caenorhabditis elegans
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18245
12 Samples
Download data: TXT
Series
Accession:
GSE137861
ID:
200137861

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Caenorhabditis elegans)

Organism:
Caenorhabditis elegans
454 Series
7801 Samples
Download data
Platform
Accession:
GPL18245
ID:
100018245

3.

daf2_D9_1

Organism:
Caenorhabditis elegans
Source name:
Whole body
Platform:
GPL18245
Series:
GSE137861
Download data: TXT
Sample
Accession:
GSM4090276
ID:
304090276

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db=gds|term=GSM4090276[Accession]|query=1|qty=2|blobid=MCID_67599293df415c74f8e0a207|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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