GSM4131257[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001391181.

HBO1 is required for the maintenance of leukaemia stem cells [shRNA screen]

(Submitter supplied) Acute myeloid leukaemia (AML) is a heterogeneous disease characterised by transcriptional dysregulation resulting in a block in differentiation and increased malignant self-renewal. Various epigenetic therapies aimed at reversing these hallmarks of AML have progressed into clinical trials, with most showing modest efficacy due to an inability to effectively eradicate leukaemia stem cells (LSC). To specifically identify novel dependencies in LSC we screened a bespoke library of small hairpin RNAs (shRNAs) targeting chromatin regulators in a unique ex vivo model of LSC. more...

Organism:: Mus musculus

Type:: Other

Platform:: GPL17021
20 Samples

Download data: CSV, TXT

Series

Accession:: GSE139118

ID:: 200139118

PubMed Similar studies SRA Run Selector

Select item 2001208132.

HBO1 is required for the maintenance of leukaemia stem cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL17021 GPL19057
36 Samples

Download data: NARROWPEAK

Series

Accession:: GSE120813

ID:: 200120813

PubMed Similar studies

Select item 1000170213.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11230 Series
301431 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3041312574.

Organism:: Mus musculus

Source name:: MLL-AF9 I-BET sensitive cells

Platform:: GPL17021
Series:: GSE120813 GSE139118

Sample

Accession:: GSM4131257

ID:: 304131257

SRA Run Selector

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GSM4131257[Accession] (4)
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