GSM4140461[Accession] - GEO DataSets

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Items: 4

Select item 2001393981.

Higher-order chromatin organization defines PR and PAX2 binding to regulate endometrial cancer cell gene expression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL18573 GPL11154 GPL16791
39 Samples

Download data: BW, NARROWPEAK, TSV

Series

Accession:: GSE139398

ID:: 200139398

PubMed Full text in PMC Similar studies

Select item 2001393932.

Higher-order chromatin organization defines PR and PAX2 binding to regulate endometrial cancer cell gene expression (RNAseq)

(Submitter supplied) Estrogen (E2) and Progesterone (Pg) via their specific receptors, ER and PR respectively, are major determinants in the development and progression of endometrial malignancies. We have studied how E2 and the synthetic progestin R5020 affect genomic function in Ishikawa endometrial cancer cells. Using ChIPseq in cells exposed to the corresponding hormones, we identified cell specific binding sites for ER (ERbs) and PR (PRbs), mostly binding to independent sites and both adjacent to PAXbs. more...