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Items: 3

1.

RNA-seq analysis of gene regulation by miR-34a and expression changes induced by DNA damage in zebrafish

(Submitter supplied) Li-Fraumeni syndrome (LFS) is a disorder due to inherited mutations in the TP53 gene resulting in an increased risk of developing several types of cancer. MicroRNA miR-34a has been implicated downstream of p53 on the basis of being a direct transcriptional target and, when over-expressed, having pro-apoptotic phenotypes in cell lines. Moreover, miR-34a has been shown to be a modifier gene in the context of LFS, since its epigenetic silencing increases the likelihood of tumour development in patients with mutant TP53. more...
Organism:
Danio rerio
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24059
12 Samples
Download data: TXT
Series
Accession:
GSE142440
ID:
200142440
2.

Ion Torrent Proton (Danio rerio)

Organism:
Danio rerio
6 Series
60 Samples
Download data
Platform
Accession:
GPL24059
ID:
100024059
3.

28 hpf wild-type treated with 1μM CPT rep3

Organism:
Danio rerio
Source name:
whole embryo
Platform:
GPL24059
Series:
GSE142440
Download data
Sample
Accession:
GSM4227406
ID:
304227406
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