GSM435059[Accession] - GEO DataSets

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Items: 4

Select item 2000174391.

Global gene-expression analyses of the Eset knock-down ES cells

(Submitter supplied) The histone H3 lysine 9 (H3K9) methyltransferase Eset is an epigenetic regulator critical for the development of the inner cell mass (ICM). Although ICM-derived embryonic stem (ES) cells are normally unable to contribute to the trophectoderm (TE) in blastocysts, we find that depletion of Eset by shRNAs leads to differentiation with the formation of trophoblast-like cells and induction of trophoblast-associated gene expression. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3599
Platform:: GPL6333
6 Samples

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Accession:: GSE17439

ID:: 200017439

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 35992.

Eset depletion effect on embryonic stem cell

Analysis of embryonic stem (ES) cells following shRNA knock-down of Eset. Eset is a histone H3 lysine 9 (H3K9) methyltransferase critical for development of the inner cell mass (ICM) from which ES cells are derived. Results provide insight into the role of Eset in ES cell differentiation.