GSM4548598[Accession] - GEO DataSets

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Items: 4

Select item 2001504031.

Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci [array]

(Submitter supplied) To better understand the fundamental molecular mechanisms that contribute to complex human diseases such as coronary artery disease (CAD), we have created a catalog of genetic variants associated with three stages of transcriptional cis-regulation in primary human coronary artery vascular smooth muscle cells. To this end, we used a pooling approach to map quantitative trait locus associations (QTLs) for TCF21 binding (ChIPseq), chromatin accessibility (ATACseq), and chromosomal looping (HiC). more...

Organism:: Homo sapiens

Type:: SNP genotyping by SNP array; Genome variation profiling by SNP array

Platform:: GPL24127
15 Samples

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Accession:: GSE150403

ID:: 200150403

PubMed Full text in PMC Similar studies

Select item 2001417522.

Quantitative trait loci mapped for TCF21 binding, chromatin accessibility and chromosomal looping in coronary artery smooth muscle cells reveal molecular mechanisms of coronary disease loci

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other; SNP genotyping by SNP array; Genome variation profiling by SNP array