GEO DataSets

(Submitter supplied) The role of many splicing factors in pre-mRNA splicing and the involvement of these factors in the processing of specific transcripts have often been defined through the analysis of loss of function mutants in vivo. Here we show that inactivating the nonsense mediated mRNA decay (NMD) results in an enhancement of splicing phenotypes associated with several splicing factors mutations. Tiling microarrays showed that inactivation of the NMD factor Upf1p in the prp17Δ and prp18Δ mutant strains reveals a larger spectrum of splicing defects than what is observed in the single mutants, including new transcripts previously shown unaffected by Prp17p or Prp18p inactivation. more...

Organism:

Saccharomyces cerevisiae

Type:

Other

Platform:

GPL9286

12 Samples

Download data: CEL

(Submitter supplied) Affymetrxi protocol

Organism:

Saccharomyces cerevisiae

1 Series

1 Related Platform

12 Samples

Download data: BPMAP