GSM4616500[Accession] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 4

Select item 2001524851.

Control of a programmed cell death pathway in Pseudomonas aeruginosa by a ppGpp-responsive antiterminator

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Pseudomonas aeruginosa PAO1

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL23999 GPL15987 GPL18782
27 Samples

Download data: BW, WIG

Series

Accession:: GSE152485

ID:: 200152485

PubMed Full text in PMC Similar studies

Select item 2001524842.

Control of a programmed cell death pathway in Pseudomonas aeruginosa by a ppGpp-responsive antiterminator [RNA-Seq]

(Submitter supplied) In the opportunistic pathogen Pseudomonas aeruginosa the alp system encodes a programmed cell death (PCD) pathway that is switched on in a subset of cells in response to DNA damage. Here we show that the central regulator of this pathway, AlpA, exerts its effects by acting as an antiterminator rather than a transcription activator. In particular, we present evidence that AlpA positively regulates the alpBCDE cell lysis genes, as well as genes in a second newly identified operon, by recognizing specific DNA sites within the promoter, then binding RNA polymerase directly and allowing it to bypass intrinsic terminators positioned downstream. more...