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Items: 3

1.

RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3’UTR required for intermediate vancomycin resistance

(Submitter supplied) Treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections is dependant on the efficacy of last-line antibiotics like vancomycin. Vancomycin treatment failure is most commonly linked to the emergence of vancomycin-intermediate resistance in clincal isolates (termed VISA). These isolates have not acquired resistance genes but appear to accumulate a heterogenous collection of single nucleotide polymerisms that collectively alter the physiology of the cell to increase vancomycin tolerance. more...
Organism:
Staphylococcus aureus subsp. aureus str. JKD6008; Staphylococcus aureus subsp. aureus str. JKD6009
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL31256 GPL29206 GPL29205
39 Samples
Download data: BEDGRAPH, GR, TSV, XLS, XLSX
Series
Accession:
GSE158830
ID:
200158830
2.

Illumina NextSeq 500 (Staphylococcus aureus subsp. aureus str. JKD6009)

Organism:
Staphylococcus aureus subsp. aureus str. JKD6009
1 Series
12 Samples
Download data
Platform
Accession:
GPL29205
ID:
100029205
3.

RNase III-CLASH negative control 1

Organism:
Staphylococcus aureus subsp. aureus str. JKD6009
Source name:
whole bacterial cells
Platform:
GPL29205
Series:
GSE158830
Download data: BEDGRAPH
Sample
Accession:
GSM4811614
ID:
304811614
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