GSM493540[Accession] - GEO DataSets

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Items: 4

Select item 2000198171.

Gene expression profiling of hypertensive and hypotensive mice

(Submitter supplied) Hypertension is a condition with major cardiovascular and renal complications, affecting nearly a billion patients worldwide. Few validated gene targets are available for pharmacological intervention, so there is a need to identify new biological pathways regulating blood pressure and containing novel targets for treatment. The genetically hypertensive “blood pressure high” (BPH), normotensive “blood pressure normal” (BPN), and hypotensive "blood pressure low" (BPL) inbred mouse strains are an ideal system to study differences in gene expression patterns that may represent such biological pathways. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS3672 GDS3673 GDS3674 GDS3675
Platform:: GPL9734
67 Samples

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Accession:: GSE19817

ID:: 200019817

Select item 36752.

Hypertension model: kidney

Analysis of kidney of genetically hypotensive BPL, normotensive BPN, and hypertensive BPH inbred strains. Results provide insight into the molecular pathways affected by hypertension in the kidney.