GSM507421[Accession] - GEO DataSets

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Items: 4

Select item 2000202471.

C-peptide and/or transforming growth factor beta 1 effect on human proximal tubular cell line

(Submitter supplied) Microarray analysis reveals up-regulation of retinoic acid and hepatocyte growth factor related signaling pathways by pro-insulin C-peptide in kidney proximal tubular cells: Antagonism of the pro-fibrotic effects of TGF-b1 Novel signaling roles for C-peptide have recently been discovered with evidence that it can ameliorate complications of type 1 diabetes. Here we sought to identify new pathways regulated by C-peptide of relevance to the pathophysiology of diabetic nephropathy. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3649
Platform:: GPL6884
18 Samples

Download data: TXT

Series

Accession:: GSE20247

ID:: 200020247

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 36492.

Proinsulin C-peptide and TGF-beta 1 effect on proximal tubular cell line: time course

Analysis of HK2 proximal tubular cells (PTCs) treated with C-peptide, TBF-beta 1, or both agents for 18 or 48 hours. C-peptide alleviates TGF-beta 1-mediated phenotypic and morphological changes in PTCs associated with epithelial-mesenchymal transformation (EMT). EMT contributes to renal fibrosis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 4 agent, 2 time sets

Platform:: GPL6884
Series:: GSE20247
18 Samples

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DataSet

Accession:: GDS3649

ID:: 3649

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000068843.

Illumina HumanWG-6 v3.0 expression beadchip

(Submitter supplied) The HumanWG-6 v3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...