GEO DataSets

(Submitter supplied) To define the sources and the extent of heterogeneity, we performed an in-depth analysis of the genomic architecture of three chemoradiation-naïve breast cancers with well-defined clinical features including variable ER, PR, Her2 receptor expression and distinct pathogenic BRCA2mut genotypes. The latter included a germ line carrier and a patient with a somatic variant. In each case we combined DNA content-based flow cytometry with whole exome sequencing and genome wide copy number variant (CNV) analysis of distinct populations sorted from multiple (4-18) mapped biopsies within the tumors and involved lymph nodes. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by array

Platform:

GPL19387

40 Samples

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(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL9777. Protocol: see manufacturer's web site at http://www.agilent.com/

Organism:

Homo sapiens

24 Series

1 Related Platform

286 Samples

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