GSM5393275[Accession] - GEO DataSets

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Items: 3

Select item 2001785161.

Expression of immune-related genes in the normal colorectal mucosa and colorectal carcinoma samples from Lynch syndrome individuals

(Submitter supplied) Colorectal carcinomas arising in the context of Lynch syndrome, the most common inherited cancer syndrome, typically show deficiency of the DNA MMR (mismatch repair) system. Lack of functional MMR leads to accumulation of frameshift mutations at micosatellites (microsatellite instability, MSI). High load of highly immunogenic tumor-specific frameshift neoantigens results in strong immune response against Lynch syndrome MSI cancers. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL27956
30 Samples

Download data: RCC

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Accession:: GSE178516

ID:: 200178516

Select item 1000279562.

NanoString Human nCounter PanCancer IO 360 Panel

(Submitter supplied) The nCounter® PanCancer IO 360 Panel includes 750 genes that cover the key pathways at the interface of the tumor, tumor microenvironment, and immune response; in addition, there are 20 internal reference genes for data normalization. Protocol: See manufacturer's website (www.nanostring.com).