GSM541788[Accession] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 4

Select item 2000217181.

Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus

(Submitter supplied) A key event in the pathogenic process of prion diseases is the conversion of the cellular prion protein (PrPC) to an abnormal and protease-resistant isoform (PrPSc). Mice lacking PrP are resistant to prion infection, and down-regulation of PrPC during prion infection prevents neuronal loss and the progression to clinical disease. These results are suggestive of the potential beneficial effect of silencing PrPC during prion diseases. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS4352
Platform:: GPL8321
14 Samples

Download data: CEL

Series

Accession:: GSE21718

ID:: 200021718

Select item 43522.

Cellular prion protein knockout effect on developing hippocampus

Analysis of hippocampi from cellular prion protein (PrPC)-deficient, FVB newborns (4.5-day-old) and adults (3-mo-old). PrPc protein is widely expressed throughout the CNS; mice lacking PrP are resistant to prion infection. Results provide insight into the influence of PrPC on the developing CNS.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 2 development stage, 2 genotype/variation sets

Platform:: GPL8321
Series:: GSE21718
14 Samples

Download data: CEL

DataSet

Accession:: GDS4352

ID:: 4352

Select item 1000083213.

[Mouse430A_2] Affymetrix Mouse Genome 430A 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...