GSM5573724[Accession] - GEO DataSets - NCBI

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Items: 3

Select item 2001839121.

CRISPR interference reveals that all-trans-retinoic acid promotes macrophage control of Mycobacterium tuberculosis by limiting bacterial access to cholesterol and propionyl-CoA

(Submitter supplied) Macrophages are a protective replicative niche for Mycobacterium tuberculosis (Mtb) but can kill the infecting bacterium when appropriately activated. To identify mechanisms of clearance, we compared bacterial restriction by human macrophages after treatment with 26 compounds, including some currently in clinical trials for tuberculosis. All-trans-retinoic acid (ATRA), an active metabolite of vitamin A, drove the greatest increase in Mtb control. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL21697
20 Samples

Download data: XLSX

Series

Accession:: GSE183912

ID:: 200183912

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000216972.

NextSeq 550 (Homo sapiens)

Organism:: Homo sapiens

1545 Series
46535 Samples

Platform

Accession:: GPL21697

ID:: 100021697

Select item 3055737243.

Organism:: Homo sapiens

Source name:: Human macrophages (MO-GMCSF)

Platform:: GPL21697
Series:: GSE183912

Sample

Accession:: GSM5573724

ID:: 305573724

SRA Run Selector

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GSM5573724[Accession] (3)
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