GEO DataSets

(Submitter supplied) This study represents the first in vivo genome wide analysis of gene epxression of Group A Streptococcus (GAS) in humans with pharyngitis. The micorarray used is a custom microarray that relies on an electrochemical reaction as the measured signal rather than flourescence. Distinct clusters of gene expression were discovered and analyzed. A functional analysis examining differences and similarities between the clusters was performed.

Organism:

Streptococcus pyogenes M1 GAS; Streptococcus pyogenes MGAS6180; Streptococcus pyogenes MGAS2096; Streptococcus pyogenes MGAS9429; Homo sapiens; Streptococcus pyogenes SSI-1; Streptococcus pyogenes MGAS5005; Streptococcus pyogenes MGAS10750; Streptococcus pyogenes MGAS315

Type:

Expression profiling by array

Platform:

GPL10562

14 Samples

Download data: TXT

(Submitter supplied) The full array layout file provided as a supplementary file. Protocol: Probe sets were 30-40mers in length, sense strand and were selected using a Combimatrix probe selection algorithm taking into account gene (>90% BLAST score) and serotype specificity, Tm, hairpins and GC content. Arrays were constructed using the CustomArray Synthesizer at Combimatrix. CustomArray uses a specially modified CMOS semiconductor to direct the molecular assembly of a specific sequence of DNA bases in response to a digital command. more...

Organism:

Streptococcus pyogenes M1 GAS; Streptococcus pyogenes SSI-1; Streptococcus pyogenes MGAS315; Streptococcus pyogenes MGAS5005; Streptococcus pyogenes MGAS6180; Streptococcus pyogenes MGAS9429; Streptococcus pyogenes MGAS2096; Streptococcus pyogenes MGAS10750

1 Series

14 Samples

Download data: TXT