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Items: 4

1.

Transcription-wide distribution of dihydrouridine (D) into mRNAs reveals its requirement for meiotic chromosome segregation.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Schizosaccharomyces pombe; Homo sapiens; Escherichia coli
Type:
Expression profiling by high throughput sequencing; Other
4 related Platforms
60 Samples
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Series
Accession:
GSE145686
ID:
200145686
2.

Transcription-wide distribution of dihydrouridine (D) into mRNAs reveals its requirement for meiotic chromosome segregation. [Rho-Seq]

(Submitter supplied) Here we have developed Rho-seq, an integrated pipeline detecting a range of modifications through differential modification-dependent Rhodamine labeling. Using Rho-seq, we report that the reduction of uridine to dihydrouridine by the Dus reductase family targets tRNAs in E. coli but expands to mRNAs is yeast. The modified mRNAs are enriched for cytoskeleton related encoded protein. We show that the a-tubulin encoding mRNA nda2 undergoes dihydrouridination, which affects its protein expression level. more...
Organism:
Schizosaccharomyces pombe; Escherichia coli; Homo sapiens
Type:
Other
4 related Platforms
44 Samples
Download data: XLSX
Series
Accession:
GSE145685
ID:
200145685
3.

Illumina NovaSeq 6000 (Schizosaccharomyces pombe)

Organism:
Schizosaccharomyces pombe
55 Series
1106 Samples
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Platform
Accession:
GPL28961
ID:
100028961
4.

pombe_dus3_R_II

Organism:
Schizosaccharomyces pombe
Source name:
S. pombe cells
Platform:
GPL28961
Series:
GSE145685 GSE145686
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Sample
Accession:
GSM5618028
ID:
305618028
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