GSM5621785[Accession] - GEO DataSets

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Items: 4

Select item 2001857081.

A hyper-quiescent chromatin state is a barrier to productive regeneration during aging.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other; Methylation profiling by high throughput sequencing

4 related Platforms
256 Samples

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Series

Accession:: GSE185708

ID:: 200185708

Select item 2001857032.

A hyper-quiescent chromatin state is a barrier to productive regeneration during aging. [CUT&Tag ]

(Submitter supplied) Epigenetic alterations are one of the key hallmarks of aging. Emerging evidence in model organisms, senescent cell cultures and limitedly, murine, and human tissue samples suggest local effects impacting genes and regulatory elements. However, how chromatin changes broadly affect euchromatin-heterochromatin balance, three-dimensional chromatin conformation, histone composition and global transcriptome has not been addressed. more...