GSM5710623[Accession] - GEO DataSets - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 3

Select item 2001899631.

Chemically synthesized guide RNAs can direct CRISPR-CasRx cleavage of circRNAs with high efficiency and specificity

(Submitter supplied) In this study, we demonstrate that CRISPR/RfxCas13d (CasRx)-mediated circRNA depletion is, for the circRNAs studied, more efficient than Argonaute 2-dependent short hairpin RNA (agoshRNA)-mediated depletion and with fewer off-target effects on the linear host RNAs. We also designed and optimally used synthetic guide RNAs (syn-gRNAs) in combination with CasRx to efficienctly deplete circRNA ciRS-7. None of the knockdown strategies tested (pre-gRNA, gRNA, syn-gRNA and agoshRNA) showed any significant off-target effects at the transcriptomics level. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL29480
24 Samples

Download data: TXT

Series

Accession:: GSE189963

ID:: 200189963

Analyze with GEO2R SRA Run Selector

Select item 1000294802.

DNBSEQ-T7 (Homo sapiens)

Organism:: Homo sapiens

152 Series
1397 Samples

Platform

Accession:: GPL29480

ID:: 100029480

Select item 3057106233.

AgoshRNA_CDR1as_KD-rep3

Organism:: Homo sapiens

Source name:: Neuroblastoma SH-SY5Y cells

Platform:: GPL29480
Series:: GSE189963

Sample

Accession:: GSM5710623

ID:: 305710623

SRA Run Selector

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Supplemental Content

Filters: Manage Filters

Find related data

Search details

Important Links

Recent activity

Clear Turn Off Turn On

GSM5710623[Accession] (3)
GEO DataSets

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets