GSM605955[Accession] - GEO DataSets

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Items: 3

Select item 2000245461.

Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias and copy number variation

(Submitter supplied) Abstract: DNA methylation is an essential epigenetic modification that plays a key role associated with the regulation of gene expression during differentiation but in disease states such as cancer, the DNA methylation landscape is often deregulated. There are now numerous technologies available to interrogate DNA methylation status of CpG sites in a targeted or genome-wide fashion but each method, due to intrinsic biases, potentially interrogates different fractions of the genome. more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array; Methylation profiling by high throughput sequencing; Genome variation profiling by SNP array

Platforms:: GPL6801 GPL9115 GPL5082
40 Samples

Download data: CEL, MAP, TXT

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Accession:: GSE24546

ID:: 200024546

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 1000050822.

[Hs_PromPR] Affymetrix Human Promoter 1.0R Array

(Submitter supplied) The GeneChip® Human Promoter 1.0R Array is designed for chromatin immunoprecipitation (ChIP) experiments. The Human Promoter Array is a single array comprised of over 4.6 million probes tiled through over 25,500 human promoter regions. Sequences used in the design of the Human Promoter array were selected from NCBI human genome assembly (Build 34). Repetitive elements were removed by RepeatMasker. Promoter regions were selected using sequence information from: 35,685 ENSEMBL genes (version 21_34d, May 14, 2004) 25,172 RefSeq mRNAs (NCBI GenBank®, February 7, 2004) 47,062 complete-CDS mRNA (NCBI GenBank, December 15, 2003) Probes are tiled at an average resolution of 35 bp, as measured from the central position of adjacent 25-mer oligos, leaving a gap of approximately 10 bp between probes. more...