GEO DataSets

(Submitter supplied) Recently, it has been demonstrated that transcriptionally active leukemia-associated fusion oncogenes alter self-renewal in and generate acute myeloid leukemia (AML) from committed progenitors, linking transformation and self-renewal pathways. AML is a heterogeneous disease, both genetically and biologically, and it is not known whether transformation is mediated by common or overlapping genetic programs downstream of multiple mutations or through the engagement of unique programs downstream of individual mutations. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS4286 GDS4439

Platform:

GPL8321

24 Samples

Download data: CEL

Analysis of granulocyte monocyte precursors (GMPs) transduced with GFP alone or with AML-fusion oncogenes MOZ-TIF2 or NUP98-HOXA9 or AML1-ETO. Results provide insight into the molecular mechanisms underlying transformation and self-renewal downstream of multiple AML-associated oncogenes.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 cell type, 5 protocol sets

Platform:

GPL8321

Series:

GSE24797

17 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A 2.0 Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...

Organism:

Mus musculus

66 DataSets

523 Series

2 Related Platforms

6974 Samples

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