GEO DataSets

(Submitter supplied) Wild type and sgs1 null yeast were grown under DNA damaging (with MMS) conditions or without treatment to log phase and their transcriptional profiles compared . The human aging diseases Werner and Bloom syndromes are a result of mutation of the WRN and BLM genes, respectively. The SGS1 gene of Saccharomyces cerevisiae is homologous to the human WRN and BLM genes of the RecQ DNA helicase family. Deletion of SGS1 results in accelerated yeast aging and a reduction in life span as well as cell cycle arrest. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS362

Platform:

GPL90

8 Samples

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Wild type and sgs1 null yeast grown with or without DNA damaging agent methyl methanesulfonate (MMS). sgs1 homologous genes linked with Bloom's and Werner's aging syndromes in humans. sgs1 mutants have high sensitivity to MMS.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent, 2 strain sets

Platform:

GPL90

Series:

GSE423

8 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 : annotation table updated with netaffx build July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Has 9335 entries and was indexed 29-Jan-2002. more...

Organism:

Saccharomyces cerevisiae

52 DataSets

166 Series

2445 Samples

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