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Items: 4

1.

A Pathobiological Role of the Insulin Receptor in CLL.

(Submitter supplied) Purpose: The chromosomal deletion 11q affects biology and clinical outcome in CLL but del11q-deregulated genes remain incompletely characterized. Results: We have identified differential expression of the insulin receptor (INSR) in CLL, including high-level INSR expression in the majority of CLL with del11q. High INSR mRNA expression in 11q CLL (~10-fold higher mean levels than other genomic categories) was confirmed by Q-PCR in 247 CLL cases. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4212
Platform:
GPL570
19 Samples
Download data: CEL, TXT
Series
Accession:
GSE26526
ID:
200026526
2.
Full record GDS4212

Chronic lymphocytic leukemia with chromosomal deletion 11q: peripheral blood CD19+ cells

Analysis of CD19+cells from peripheral blood of chronic lymphocytic leukemia (CLL) patients with interstitial deletions on the long arm of chromosome 11 (del11q). Del11q is associated with progressive and aggressive CLL. Results provide insight into the molecular pathogenesis of CLL with del11q.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 other sets
Platform:
GPL570
Series:
GSE26526
19 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5671 Series
61 Related Platforms
175585 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

CLL_del11q rep2_case24

Organism:
Homo sapiens
Source name:
flow-sorted CD19+ cells from peripheral blood of chronic lymphocytic leukemia patient; del11q present.
Platform:
GPL570
Series:
GSE26526
Dataset:
GDS4212
Download data: CEL
Sample
Accession:
GSM652230
ID:
300652230
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db=gds|term=GSM652230[Accession]|query=1|qty=2|blobid=MCID_675b35e2b80ed315f11eddc8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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