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Items: 4

1.

Identification of Growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a Novel Tumor Suppressor in Pituitary Gonadotrope Tumors

(Submitter supplied) Gonadotrope or null cell pituitary tumors present clinically with signs of hypogonadism and hypopituitarism, together with visual disturbances due to mass effects. Since there are no medical therapies, surgery and/or radiation are the only therapeutic options. To identify dysregulated genes and/or pathways that may play a role in tumorigenesis and/ or progression, molecular profiling was performed on 14 gonadotrope tumors and 9 normal human pituitaries from autopsy samples. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4275
Platform:
GPL570
23 Samples
Download data: CEL
Series
Accession:
GSE26966
ID:
200026966
2.
Full record GDS4275

Pituitary gonadotrope tumors

Analysis of gonadotrope/null cell tumors and normal pituitaries from autopsy samples. Pituitary gonadotrope tumors cause significant morbidity, hormonal deficits, and are more common in men. Results provide insight into molecular mechanisms involved in pituitary tumorigenesis and progression.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 3 disease state, 2 gender sets
Platform:
GPL570
Series:
GSE26966
23 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5671 Series
61 Related Platforms
175585 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

T034, human gonadotrope/null cell tumor, biological rep 10

Organism:
Homo sapiens
Source name:
Human gonadotrope/null cell tumor collected at the time of transsphenoidal surgery
Platform:
GPL570
Series:
GSE26966
Dataset:
GDS4275
Download data: CEL
Sample
Accession:
GSM663754
ID:
300663754
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