GSM67066[Accession] - GEO DataSets

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Items: 4

Select item 2000030551.

Sex-specific role of Drosophila HP1 in regulating chromatin structure and gene transcription

(Submitter supplied) Drosophila heterochromatin protein 1- HP11 is believed to be involved in active transcription, transcriptional gene silencing, and the formation of heterochromatin2-7. However, little is known about the function of HP1 during development. Using a Gal4-induced RNA interference system, we show that conditional depletion of HP1 in transgenic flies results in preferential lethality in male flies. Cytological analysis of mitotic chromosomes reveals that HP1 depletion causes sex-biased chromosomal defects, including telomere fusions. more...

Organism:: Drosophila melanogaster

Type:: Expression profiling by array

Dataset:: GDS1526
Platform:: GPL1322
11 Samples

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Series

Accession:: GSE3055

ID:: 200003055

Select item 15262.

Heterochromatin protein HP-1 depletion effect on third instar larvae

Analysis of male and female 3rd instar larvae following depletion of heterochromatin protein 1 (HP1) using a Gal4-induced RNA interference system. Results provide insight into the function of HP1 during development and a sex-specific role.

Organism:: Drosophila melanogaster

Type:: Expression profiling by array, transformed count, 2 gender, 3 genotype/variation, 2 protocol sets

Platform:: GPL1322
Series:: GSE3055
11 Samples

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DataSet

Accession:: GDS1526

ID:: 1526

Select item 1000013223.

[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Drosophila Genome 2.0 Array is a microarray tool for studying expression of Drosophila melanogaster transcripts: - Provides comprehensive coverage of the transcribed Drosophila genome on a single array - Comprised of 18,880 probe sets, analyzing over 18,500 transcripts Sequences used in the design of the GeneChip Drosophila Genome 2.0 Array were selected from Flybase version 3.1. more...