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Items: 4

1.

Significant Effects of Antiretroviral Therapy on Global Gene Expression in Brain Tissues of Patients with HIV-Associated Neurocognitive Disorders

(Submitter supplied) Antiretroviral therapy (ART) has reduced morbidity and mortality in HIV infection; however HIV-1-associated neurocognitive disorders (HAND) persist despite treatment. We used microarray analysis in post-mortem brain tissues to determine ART effectiveness in the brain and to identify molecular signatures of HAND under ART.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4231
Platform:
GPL570
35 Samples
Download data: CEL
Series
Accession:
GSE28160
ID:
200028160
2.
Full record GDS4231

Antiretroviral therapy effect on brain of patients with HIV-associated neurocognitive disorders

Analysis of postmortem brain of ART-treated, HIV-1-associated neurocognitive disorders (HAND) patients. ART reduces morbidity and mortality in HIV infection, but HAND persist despite treatment. Results provide insight into ART effectiveness in brain and into molecular signatures of HAND under ART.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 agent, 2 disease state sets
Platform:
GPL570
Series:
GSE28160
35 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5670 Series
61 Related Platforms
175576 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

Control brain 4, biological rep2

Organism:
Homo sapiens
Source name:
Homo sapiens postmortem brain tissue
Platform:
GPL570
Series:
GSE28160
Dataset:
GDS4231
Download data: CEL
Sample
Accession:
GSM697487
ID:
300697487
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