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Items: 4

1.

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL17021 GPL16791 GPL21311
170 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE226003
ID:
200226003
2.

Disruption of RNAPII transcription elongation links Oncogenic splicing factor mutations to replciation stress and targetable alterations in chromatin landscape [Long read sequencing]

(Submitter supplied) To understand how SF3B1K700E impacts co-transcriptional splicing, we peformed long read sequencing of RNA (nSRS-seq) in K562 cells (wild type and SF3B1K700E mutant) at 4 days after mutant allele expression We then performed co-transcriptional splicing efficiency analysis using data obtained from Long read sequencing
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21311
4 Samples
Download data: TXT
Series
Accession:
GSE225992
ID:
200225992
3.

PacBio RS II (Homo sapiens)

Organism:
Homo sapiens
19 Series
119 Samples
Download data
Platform
Accession:
GPL21311
ID:
100021311
4.

K562 cells, SF3B1 K700E, 4 days, replicate 1 [LRSseq]

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL21311
Series:
GSE225992 GSE226003
Download data: TXT
Sample
Accession:
GSM7061460
ID:
307061460
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Supplemental Content

db=gds|term=GSM7061460[Accession]|query=1|qty=3|blobid=MCID_674c2b80d8260840384cb851|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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