GSM707593[Accession] - GEO DataSets

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Items: 3

Select item 2000285801.

RNA interference screening identifies the Insulin/IGF-1 receptor pathway as a mechanism of escape from hormone dependence in breast cancer

(Submitter supplied) A significant fraction of breast cancers exhibit de novo or acquired resistance to estrogen deprivation. A kinome-wide siRNA screen identified a role for Insulin Receptor (InsR) in the hormone-independent growth of ER+ breast cancer cells We used gene expression microarrays to identify genes and pathways that are altered by insulin stimulation of ER+ MCF-7 human breast cancer cells.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL13158
9 Samples

Download data: CEL, CHP

Series

Accession:: GSE28580

ID:: 200028580

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000131582.

[HT_HG-U133_Plus_PM] Affymetrix HT HG-U133+ PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Annotations derived from HT_HG-U133_Plus_PM.na31.annot.csv Protocol: see manufacturer's web site