GSM7140685[Accession] - GEO DataSets

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Items: 3

Select item 2002288511.

Gene expression under short-term moderate hypoxia and in the HIF-1 negative regulator mutants in Caenorhabditis elegans

(Submitter supplied) Hypoxia inducible transcription factor HIF is the master regulator of hypoxia response in metazoans. The stability and activity of HIF are tightly regulated. In the model organism C. elegans, the homolog of HIF is HIF-1. The stability and activity of HIF-1 are negatively regulated by vhl-1, egl-9, rhy-1 and swan-1 when HIF-1 is stabilized by vhl-1 mutation. Here, we are using Affymetrix microarray to measure the immediate gene expression changes under short-term hypoxia treatment (2 hours of 0.5% oxygen treatment). more...

Organism:: Caenorhabditis elegans

Type:: Expression profiling by array

Platform:: GPL200
24 Samples

Download data: CEL

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Accession:: GSE228851

ID:: 200228851

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000002002.

[Celegans] Affymetrix C. elegans Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Has 22625 entries and was indexed 30-Apr-2002. Sequence information used for the design of the C. elegans array was downloaded from the Sanger Center database on December 05, 2000 and from GenBank release 121. All sequences were functionally reannotated by Affymetrix for improved descriptions. more...