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Items: 3

1.

Expression Profiles of HepG2 cells treated with genotoxic and non-genotoxic agents

(Submitter supplied) The lack of accurate in vitro assays for predicting in vivo toxicity of chemicals together with new legislations demanding replacement and reduction of animal testing has triggered the development of alternative methods. This study aimed at developing a transcriptomics-based in vitro prediction assay for in vivo genotoxicity. The transcriptomics changes induced in the human liver cell line HepG2 by 34 compounds after treatment for 12h, 24h and 48h were used for the selection of gene-sets that can discriminate between in vivo genotoxins (GTX) and in vivo non-genotoxins (NGTX). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL9101
560 Samples
Download data: CEL
Series
Accession:
GSE28878
ID:
200028878
2.

Affymetrix GeneChip Human Genome U133 Plus 2.0 Array (MBNI v11 Entrez Gene ID CDF)

(Submitter supplied) see the Affymetrix website
Organism:
Homo sapiens
4 Series
1 Related Platform
720 Samples
Download data: TAR, ZIP
Platform
Accession:
GPL9101
ID:
100009101
3.

Serie H, HepG2 exposed to MOCA for 24h, biological rep 1

Organism:
Homo sapiens
Source name:
hepatocellular carcinoma cell line
Platform:
GPL9101
Series:
GSE28878
Download data: CEL
Sample
Accession:
GSM715116
ID:
300715116
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Supplemental Content

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