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Items: 4

1.

TMPRSS2-ERG, HDACs and EZH2 are involved in an AR-centric transcriptional circuitry that calibrates androgenic response for prostate cancer progression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL9115 GPL10558 GPL6883
27 Samples
Download data: BED, TXT
Series
Accession:
GSE28951
ID:
200028951
2.

TMPRSS2-ERG, HDACs and EZH2 are involved in an AR-centric transcriptional circuitry that calibrates androgenic response for prostate cancer progression (gene expression data)

(Submitter supplied) Deregulation of the Androgen Receptor (AR) transcriptional network is a common hallmark in prostate cancers. To achieve its precise transcriptional role, AR needs to co-operate specifically with a plethora of cofactors. In prostate cancers, AR transcription collaborators are frequently aberrantly over-expressed, altering the AR signaling pathway to one that promotes oncogenesis. Recently, the prostate cancer recurrent fusion gene, ERG, was shown to promote tumor progression by acting as a repressor of AR signaling. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
8 Samples
Download data: TXT
Series
Accession:
GSE28948
ID:
200028948
3.

Illumina HumanRef-8 v3.0 expression beadchip

(Submitter supplied) The HumanRef-8 v3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...
Organism:
Homo sapiens
8 DataSets
229 Series
3 Related Platforms
7128 Samples
Download data: BGX
Platform
Accession:
GPL6883
ID:
100006883
4.

VCAP, 24h 10nM DHT

Organism:
Homo sapiens
Source name:
VCaP prostate cancer cells, 24h DHT
Platform:
GPL6883
Series:
GSE28948 GSE28951
Download data
Sample
Accession:
GSM717374
ID:
300717374
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Supplemental Content

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