GSM718843[Accession] - GEO DataSets

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Items: 5

Select item 2000290151.

Gene expression analyses of mice selectively inbred for trait anxiety

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Datasets:: GDS4001 GDS4002
Platforms:: GPL6481 GPL7467
148 Samples

Download data: TXT

Series

Accession:: GSE29015

ID:: 200029015

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000290142.

Gene expression profiling of high (HAB) vs. low (LAB) and normal (NAB) anxiety-related behavior mice in five laser microdissected brain regions.

(Submitter supplied) Investigating the molecular basis and correlates of anxiety-related and depression-like behaviors, we generated a mouse model consisting of high (HAB), normal (NAB) and low (LAB) anxiety-related behavior mice. We utilized the elevated plus-maze for testing the genetic predisposition to anxiety-related behavior and, consequently, used this as selection criterion for the inbreeding of our animals. In depression-related tests, HAB mice display a more passive, depression-like coping strategy than LAB mice, resembling clinical comorbidity of anxiety and depression as observed in psychiatric patients. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL6481
78 Samples

Download data: TXT

Series

Accession:: GSE29014

ID:: 200029014

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 40023.

High, Normal, and Low Anxiety: multiple brain regions

Analysis of five brain regions closely connected to the emotion-regulating parts of the limbic system, isolated by LCM from CD-1 males selectively bred for high (HAB), normal (NAB), or low (LAB) anxiety-related behavior. Results provide insight into the molecular mechanisms underlying anxiety.