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Items: 4

1.

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T-cell acute lymphoblastic leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL13232 GPL9115 GPL11154
64 Samples
Download data: CEL, WIG, YLF
Series
Accession:
GSE29181
ID:
200029181
2.

Identification of differentially expressed genes upon shRNA knockdown of TAL1 and its regulatory partners in T-ALL cells (Jurkat)

(Submitter supplied) The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify the core transcriptional regulatory circuit controlled by TAL1 and its regulatory partners HEB, E2A, GATA3, ETS1 and RUNX1 in T-ALL cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL13232
32 Samples
Download data: CEL
Series
Accession:
GSE29179
ID:
200029179
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray RefSeq Version 13.0.0]

(Submitter supplied) This is identical to GPL570 but a custom CDF environment was used to extract data [Brainarray Version 13.0.0, HGU133Plus2_Hs_REFSEQ]. CDF and other files can be downloaded at: http://brainarray.mbni.med.umich.edu/Brainarray/Database/CustomCDF/13.0.0/refseq.asp Protocol: see manufacturer's web site
Organism:
Homo sapiens
3 Series
1 Related Platform
36 Samples
Download data
Platform
Accession:
GPL13232
ID:
100013232
4.

E2A_shRNA1_Jurkat, biological replicate2

Organism:
Homo sapiens
Source name:
Jurkat cells transduced with TCF3/E2A shRNA1 for 72 hrs
Platform:
GPL13232
Series:
GSE29179 GSE29181
Download data: CEL
Sample
Accession:
GSM722145
ID:
300722145
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Supplemental Content

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