GEO DataSets

(Submitter supplied) Chronic high flow can induce arterial remodeling, and this effect is mediated by endothelial cells (ECs) responding to wall shear stress (WSS). To assess how WSS above physiological normal levels affects ECs, we used DNA microarrays to profile EC gene expression under various flow conditions. Cultured bovine aortic ECs were exposed to no flow (0 Pa), normal WSS (2 Pa) and very high WSS (10 Pa) for 24 hrs. more...

Organism:

Bos taurus

Type:

Expression profiling by array

Dataset:

GDS4525

Platform:

GPL2112

9 Samples

Download data: CEL

Analysis of aortic endothelial cells (EC) exposed to high wall shear stress (WSS) for 24hr in an in vitro flow loop system. High WSS often induces expansive remodeling of the artery. Results provide insight into the molecular mechanisms underlying adaptive remodeling under high WSS conditions.

Organism:

Bos taurus

Type:

Expression profiling by array, transformed count, 3 stress sets

Platform:

GPL2112

Series:

GSE29376

9 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Bovine Genome Array can be used to study gene expression of over 23,000 bovine transcripts. The array is an ideal tool for researchers studying gene expression profiles in cattle. With the broadest representation of publicly available expressed sequence information, bovine researchers will be able to use this array to monitor genetic mechanisms regulating a variety of preferred traits, such as: - Disease resistance - Meat and dairy production - Stress tolerance The Bovine Genome Array was designed in close collaboration with the Bovine Research Community as part of the Affymetrix GeneChip Consortia Program. more...

Organism:

Bos taurus

8 DataSets

134 Series

3 Related Platforms

2304 Samples

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