GSM7509861[Accession] - GEO DataSets

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Items: 4

Select item 2002358081.

Mapping the dynamics of epigenetic adaptation during heterochromatin misregulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Schizosaccharomyces pombe

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL28961 GPL16192 GPL20584
126 Samples

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Accession:: GSE235808

ID:: 200235808

Select item 2002358072.

Mapping the dynamics of epigenetic adaptation during heterochromatin misregulation [RNA-seq]

(Submitter supplied) Stress can spur the redistribution of histone modifications to establish novel phenotypes. We do not understand how cells leverage existing epigenetic pathways to establish and maintain new gene expression states that enhance fitness and cell survival. H3K9 methylation promotes epigenetic silencing in fission yeast (S. pombe). Heterochromatin establishment depends on the H3K9 methyltransferase, Clr4 and is opposed by two major two heterochromatin regulators, Epe1, a putative H3K9 demethylase and Mst2, an H3K14 acetyltransferase. more...