GSM757757[Accession] - GEO DataSets

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Items: 4

Select item 2000305431.

Differential gene expression profiles between SUM149 cells transfected with control siRNA and SUM149 cells transfected with siRNA targeting tarzarotene-induced gene 1 (TIG1)

(Submitter supplied) We identified tazarotene-induced gene 1 (TIG1) as a potential tumorigenic gene in IBC. To investigate the underlying mechanism by which TIG1 promotes tumor growth and invasiveness of IBC cells, we first sought to identify TIG1 functional partners by using DNA microarray analysis to compare gene expression profiles between SUM149 cells transfected with control siRNA and SUM149 cells transfected with siRNA targeting TIG1. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4818
Platform:: GPL570
6 Samples

Download data: CEL

Series

Accession:: GSE30543

ID:: 200030543

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 48182.

Inflammatory breast cancer cell line response to TIG1 depletion

Analysis of SUM149 inflammatory breast cancer (IBC) cells depleted for TIG1. TIG1 depletion decreased IBC cell proliferation, migration, and invasion in vitro and inhibited tumor growth of IBC cells in vivo. Results provide insight into the role of TIG1 in the pathogenesis and progression of IBC.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 genotype/variation sets

Platform:: GPL570
Series:: GSE30543
6 Samples

Download data: CEL

DataSet

Accession:: GDS4818

ID:: 4818

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...