GSM758870[Accession] - GEO DataSets

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Items: 4

Select item 2000305931.

A unique iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Candida albicans

Type:: Expression profiling by array; Genome binding/occupancy profiling by array

Platforms:: GPL13696 GPL13813
32 Samples

Download data: GPR

Series

Accession:: GSE30593

ID:: 200030593

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000305902.

A unique iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis [Expression Array]

(Submitter supplied) The mammalian gastrointestinal tract and the bloodstream are highly disparate biological niches, and yet certain commensal-pathogenic microorganisms are able to thrive in both environments. Here, we report the evolution of a unique transcription circuit in the yeast, Candida albicans, which determines its fitness in both host niches. Our comprehensive analysis of the DNA-binding proteins that regulate iron uptake by this organism suggests the evolutionary intercalation of a transcriptional activator called Sef1 between two broadly conserved transcriptional repressors, Sfu1 and Hap43. more...

Organism:: Candida albicans

Type:: Expression profiling by array

Platform:: GPL13813
22 Samples

Download data: GPR

Series

Accession:: GSE30590

ID:: 200030590

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000138133.

Agilent-020166 Candida albicans 8 x 15k Custom Expression Array v2

(Submitter supplied) A unique iron homeostasis regulatory circuit with reciprocal roles in Candida albicans commensalism and pathogenesis. Suzanne Noble lab --- Candida albicans - 8 x 15k Agilent ID020166 Expression Array v2 Genome version: Assembly 19; 24-Aug-2009; http://www.candidagenome.org/download/sequence/ 60-mer oligonucleotides. Protocol: Arrays were custom designed Agilent 8*15k Microarrays [AMADID #020166] containing a minimum of 2 independent probes for each ORF. more...