GEO DataSets

(Submitter supplied) Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, while evidence supports the replicative capacity of adult beta cells in vivo, attempts at expanding human islet cells in tissue culture resulted in loss of beta-cell phenotype. Using a genetic lineage-tracing approach we have provided evidence for massive proliferation of beta-cell-derived (BCD) cells within these cultures. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3984

Platform:

GPL6244

11 Samples

Download data: CEL

Analysis of insulin-producing cells generated from expanded dedifferentiated islet cells induced with Redifferentiation Cocktail (RC). Results provide insight into molecular mechanisms underlying RC-induced phenotypic change in expanded islet cells towards the phenotype of uncultured islet cells.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 cell type, 3 growth protocol sets

Platform:

GPL6244

Series:

GSE30732

11 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Homo sapiens

136 DataSets

1879 Series

27 Related Platforms

38399 Samples

Download data