GSM7692525[Accession] - GEO DataSets

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Items: 4

Select item 2002402951.

Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL21273
60 Samples

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Accession:: GSE240295

ID:: 200240295

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Select item 2002402942.

Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles [mirna-seq]

(Submitter supplied) Microglia are resident immune cells of the brain that play important roles in mediating inflammatory responses in several neurological diseases via direct and indirect mechanisms. One indirect mechanism may involve extracellular vesicle (EV) release, so that the molecular cargo transported by microglia-derived EVs can have functional effects by facilitating intercellular communication. The molecular composition of microglia-derived EVs, and how microglial activation states impacts EV composition and EV-mediated effects in neuroinflammation, remain poorly understood. more...