GSM7749245[Accession] - GEO DataSets

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Items: 4

Select item 2002421231.

Systematic Perturbation of Thousands of Retroviral LTRs in Mouse Embryos

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24247
24 Samples

Download data: BW

Series

Accession:: GSE242123

ID:: 200242123

PubMed Full text in PMC Similar studies

Select item 2002421212.

Systematic Perturbation of Thousands of Retroviral LTRs in Mouse Embryos [RNA-Seq]

(Submitter supplied) In mammals, many retrotransposons are de-repressed during zygotic genome activation (ZGA). However, their functions in early development remain elusive largely due to the challenge to simultaneously manipulate thousands of retrotransposon insertions in embryos. Here, we employed epigenome editing to perturb long terminal repeat (LTR) MT2_Mm, a well-known ZGA and totipotency marker that exists in ~2667 insertions throughout the mouse genome. more...