GSM7807468[Accession] - GEO DataSets

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Items: 4

Select item 2002441231.

Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL24676 GPL30991 GPL24247
103 Samples

Download data: DCC, H5, TAR

Series

Accession:: GSE244123

ID:: 200244123

Select item 2002441172.

Olfactory neuroblastoma mimics molecular subtypes and lineage trajectories of small cell lung cancer [Spatial transcriptomics on de-identified human ONB samples]

(Submitter supplied) The olfactory epithelium relies on active neuron regeneration from basal stem cells and is susceptible to olfactory neuroblastoma (ONB), a rare, aggressive tumor of unclear origins. Here, we establish a new, highly-penetrant, genetically-engineered mouse model of ONB with alterations in Rb1/Trp53/Myc that exhibit a NEUROD1+ immature neuronal state. ASCL1 loss leads to emergence of non-neuronal histopathologies, including a POU2F3+ microvillar-like state. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL30991
96 Samples

Download data: DCC

Series

Accession:: GSE244117

ID:: 200244117

Select item 1000309913.

NanoString GeoMx Human Whole Transcriptome Atlas [do not use this platform, see NOTE below]

(Submitter supplied) Human RNA for Illumina Systems. RNA Probe set that targets 18,000+ transcripts for human protein-coding genes plus ERCC negative controls to profile the whole transcriptome. Excludes uninformative high expressing targets such as ribosomal subunits. Includes RNA probes designed for Illumina NGS readout with the Seq Code library prep. *** IMPORTANT NOTE ***: For NanoString GeoMx Digital Spatial Profiling studies with raw data in FASTQ format, please submit your study using GEO's high throughput sequence data submission instructions at: https://www.ncbi.nlm.nih.gov/geo/info/seq.html Protocol: See NanoString web site.