GSM7835586[Accession] - GEO DataSets

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Items: 4

Select item 2002450871.

Topoisomerase I (TOP1) is a functional mitotic interactor of the bookmarking factor HNF1B

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL19415 GPL19057 GPL18573
43 Samples

Download data: RESULTS

Series

Accession:: GSE245087

ID:: 200245087

PubMed

Select item 2002450702.

Topoisomerase I (TOP1) is a functional mitotic interactor of the bookmarking factor HNF1B [ChIPseq_KEC]

(Submitter supplied) HNF1B (Hepatocyte Nuclear Factor 1-Beta) is a POU-homeobox transcription factor expressed in kidney and frequently mutated in patients suffering from Congenital Anomalies of the Kidney and the Urinary Tract (CAKUT). HNF1B is a bookmarking factor, able to bind mitotic chromatin and necessary for the post-mitotic reactivation of gene expression. In order to characterize the molecular functions of HNF1B as a bookmarking factor, we performed ChIPseq on asynchronous and mitotic renal cells. more...