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Items: 4

1.

ZEBOV-induced changes in macrophage gene expression

(Submitter supplied) Zaire ebolavirus (ZEBOV) infections are associated with high lethality in primates. ZEBOV primarily targets mononuclear phagocytes, which are activated upon infection and secrete mediators believed to trigger initial stages of pathogenesis. The characterization of the responses of target cells to ZEBOV infection may therefore not only further understanding of pathogenesis but also suggest possible points of therapeutic intervention. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4356
Platform:
GPL8300
12 Samples
Download data: CEL, CHP
Series
Accession:
GSE31747
ID:
200031747
2.
Full record GDS4356

Zaire ebolavirus infection of macrophage: time course

Analysis of primary macrophages from three donors (D1, D2, D3) up to 6 hrs after in vitro exposure to purified Zaire ebolavirus (ZEBOV) virions. ZEBOV is the etiological agent of Ebola Hemorrhagic Fever (EHF). Results provide insight into the initial response of macrophages exposed to Ebola virions.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 individual, 2 infection, 2 time sets
Platform:
GPL8300
Series:
GSE31747
12 Samples
Download data: CEL, CHP
3.

[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes. more...
Organism:
Homo sapiens
99 DataSets
302 Series
6446 Samples
Download data
Platform
Accession:
GPL8300
ID:
100008300
4.

Donor 1, Ebola infected 6hr

Organism:
Homo sapiens
Source name:
Ebola-infected macrophages harvested at 6h post-treatment from donor 1
Platform:
GPL8300
Series:
GSE31747
Dataset:
GDS4356
Download data: CEL, CHP
Sample
Accession:
GSM787943
ID:
300787943
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