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Items: 3

1.

A novel inhibitor of P. aeruginosa folate metabolism exploits metabolic differences for narrow-spectrum antibiotic targeting

(Submitter supplied) Pseudomonas aeruginosa is a leading cause of hospital acquired infections for which the development of new antibiotics is urgently needed. Unlike most enteric bacteria, P. aeruginosa lacks thymidine kinase and thymidine phosphorylase activity, and thus cannot scavenge exogenous thymine. An appealing strategy to selectively target P. aeruginosa while leaving the healthy microbiome largely intact would thus be to disrupt thymidine synthesis while providing exogenous thymine. more...
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33271
3 Samples
Download data: XLSX
Series
Accession:
GSE249862
ID:
200249862

PubMed Full text in PMC Similar studies

2.

NextSeq 2000 (Pseudomonas aeruginosa)

Organism:
Pseudomonas aeruginosa
6 Series
45 Samples
Download data
Platform
Accession:
GPL33271
ID:
100033271

3.

MexEF oprN efflux pump mutant

Organism:
Pseudomonas aeruginosa
Source name:
bacteria
Platform:
GPL33271
Series:
GSE249862
Download data
Sample
Accession:
GSM7966053
ID:
307966053

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db=gds|term=GSM7966053[Accession]|query=1|qty=2|blobid=MCID_67694e8e7eb86f557f849db9|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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