GEO DataSets

(Submitter supplied) Models for tumorigenesis can be made by transforming normal cells with defined genetic elements. This allows us to determine that adrenocortical tumor development and progression follows a multistep model. Morever, we demonstrated that the order of genetic events has a great consequence on the phenotype of the resultant tumor. We performed transcriptomic analysis using cDNA microarrays to identify the molecular signature that might explain the distinctive in vivo phenotypes observed in response to both orders of the mutational events.

Organism:

Bos taurus

Type:

Expression profiling by array

Dataset:

GDS4520

Platform:

GPL2112

9 Samples

Download data: CEL, CHP, TXT

Analysis of primary adrenocortical cells transduced with oncogenic Ras and a truncated form of p53. The acquisition order of the genetic alterations results in distinct adrenocortical tumor (ACT) phenotypes. Results provide insight into the molecular mechanisms underlying ACT pathogenesis.

Organism:

Bos taurus

Type:

Expression profiling by array, count, 4 protocol sets

Platform:

GPL2112

Series:

GSE32305

9 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Bovine Genome Array can be used to study gene expression of over 23,000 bovine transcripts. The array is an ideal tool for researchers studying gene expression profiles in cattle. With the broadest representation of publicly available expressed sequence information, bovine researchers will be able to use this array to monitor genetic mechanisms regulating a variety of preferred traits, such as: - Disease resistance - Meat and dairy production - Stress tolerance The Bovine Genome Array was designed in close collaboration with the Bovine Research Community as part of the Affymetrix GeneChip Consortia Program. more...

Organism:

Bos taurus

8 DataSets

134 Series

3 Related Platforms

2304 Samples

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