GSM807858[Accession] - GEO DataSets

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Items: 4

Select item 2000325921.

Human and mouse lupus nephritis cross-species transcriptional analysis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by array

Platforms:: GPL14663 GPL7546
150 Samples

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Series

Accession:: GSE32592

ID:: 200032592

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000325912.

Expression data from human with lupus nephritis (LN)

(Submitter supplied) Nephritis (LN) is a serious manifestation of SLE. Therapeutic studies in mouse LN models do not always predict outcomes of human therapeutic trials, raising concerns about the human relevance of these models. In this study we used an unbiased transcriptional network approach to define similarities and differences between three lupus models and human LN. Affymetrix-based expression profiles were analyzed using Genomatix Bibliosphere software and transcriptional networks were compared using the Tool for Approximate LargE graph matching (TALE). more...