GEO DataSets

(Submitter supplied) IL-17C is important for the pathogenesis of inflammatory diseases such as IBD and psoriasis. We found that IL-17C is highly induced in a murine model of psoriasis. Recent results suggest that IL-17C can target epithelial cells that express both IL-17RA and IL-17RE receptor chains. Here we identify genes induced in response to IL-17C treatment of human keratinocytes to provide the tools for dissection of the IL-17C signaling pathway.

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4807

Platform:

GPL6480

16 Samples

Download data: TXT

Analysis of keratinocytes treated with Interleukin 17C (IL-17C) for 3 and 24 hours. IL-17C is induced in epithelia by bacterial challenge and inflammatory stimuli and upregulated in psoriatic skin lesions. Results provide insight into the role of IL-17C in the innate epithelial immune response.

Organism:

Homo sapiens

Type:

Expression profiling by array, log2 ratio, 2 agent, 2 time sets

Platform:

GPL6480

Series:

GSE32620

16 Samples

Download data: TXT

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...

Organism:

Homo sapiens

21 DataSets

944 Series

4 Related Platforms

24905 Samples

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