GSM816595[Accession] - GEO DataSets

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Items: 4

Select item 2000329791.

Cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array

Platforms:: GPL6982 GPL6102
94 Samples

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Accession:: GSE32979

ID:: 200032979

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000329692.

Genome-wide SNP analysis of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients

(Submitter supplied) The risk of developing cutaneous squamous cell carcinoma (SCC) is markedly increased in organ transplant recipients (OTRs) compared to the normal population. Next to sun exposure, the immunosuppressive regimen is an important risk factor for SCC development in OTRs. Various gene mutations (e.g. TP53) and genetic alterations (e.g. CDKN2A loss, RAS amplification) have been found in SCCs. The aim of this study was to identify genomic alterations that are consistently involved in the formation of SCCs and their precursor lesions, actinic keratoses (AKs). more...