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Items: 3

1.

Monitoring of melanoma patients on treatment reveals a distinct macrophage population driving targeted therapy resistance

(Submitter supplied) Resistance to targeted therapy remains a major clinical challenge in melanoma patients. To uncover resistance mechanisms, we performed single cell RNA sequencing of fine needle aspirates from resistant and responding tumors from melanoma patients before and during BRAFi/MEKi treatment. Among the genes most differentially expressed between malignant cells from resistant vs. responding tumors was POSTN encoding the secreted factor periostin. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL34284
10 Samples
Download data: TXT
Series
Accession:
GSE262779
ID:
200262779
2.

Illumina NovaSeq X Plus (Homo sapiens)

Platform
Accession:
GPL34284
ID:
100034284
3.

43_MEKi.SPP1.CD44_2

Organism:
Homo sapiens
Source name:
M150543
Platform:
GPL34284
Series:
GSE262779
Download data
Sample
Accession:
GSM8178815
ID:
308178815
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db=gds|term=GSM8178815[Accession]|query=1|qty=2|blobid=MCID_674c491a96d9ad0406241222|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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